International Research
Research projects in SCN2A from around the world have been collated here.
Latest Posts
Computational analysis of 10,860 phenotypic annotations in individuals with SCN2A-related disorders
December 31, 2021
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Using computational analysis common symptoms for 5 phenotypes of SCN2A were found. The model also predicted gain & loss of function variants.
SCN2A severe hypomorphic mutation decreases excitatory synaptic input and causes autism-associated behaviors
December 22, 2021
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This study showed a direct relationship between autism behaviour and SCN2A loss of function mutation in a mouse model.
Generation and basic characterization of a gene-trap knockout mouse model of SCN2A
December 8, 2021
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This study found behaviour abnormalities in SCN2A mouse models that can be used to assess the effectiveness of new treatments.
SCN2A International Natural History Study
July 18, 2021
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Help understand SCN2A by enrolling in this natural history study which is open to participants from any country.